Hold down button to automatically inject medicine–it clicks when starting and stopping
Locking mechanism prevents you from starting injection accidentally
Large window gives clear view of medicine
Wide grip with rubber-lined sides helps with holding the Pen
Hold down button to automatically inject medicine–it clicks when starting and stopping
Locking mechanism prevents you from starting injection accidentally
Large window gives clear view of medicine
Wide grip with rubber-lined sides make it easy to hold
Watch the full video. Then choose a specific step from the menu above to watch any of sections again.
SUPER/VOICEOVER (V.O.):
This demonstration is a guide to injecting with the SKYRIZI Pen.
Watch it and also read the entire SKYRIZI Instructions for Use leaflet, inserted with your medication package.
Don’t try to inject SKYRIZI until your doctor has decided you can, and you’ve been shown the right way to inject.
SUPER:
[SKYRIZI logo]
Please see Use and Important Safety Information at the end of this video.
Please see link for the full Prescribing Information, including the Medication Guide, for SKYRIZI.
SUPER/V.O.:
SKYRIZI® (risankizumab-rzaa) USES
SKYRIZI is a prescription medicine used to treat adults:
- with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).
- with active psoriatic arthritis (PsA).
SAFETY CONSIDERATIONS
SKYRIZI may cause serious side effects, including:
- Serious allergic reactions: Stop using SKYRIZI and get emergency medical help right away if you get any symptoms of a serious allergic reaction.
- Infections: SKYRIZI may increase your risk of infections. Before starting treatment, your doctor should check you for infections and tuberculosis. Tell your doctor right away if you have an infection or symptoms of one.
Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI.
Also, tell your doctor if you plan to or recently received a vaccine.
[SKYRIZI logo]
Please see Use and Important Safety Information at the end of this video.
Please see link for the full Prescribing Information, including the Medication Guide, for SKYRIZI.
SUPER:
A GUIDE TO INJECTING WITH SKYRIZI
[SKYRIZI logo]
[SKYRIZI Complete logo]
PATIENT V.O.:
Hi, I’m Michael. And I’m here to show you how to inject using a SKYRIZI Pen.
SUPER:
MICHAEL
PATIENT V.O.:
I’ve been doing this for a while now, and I feel like I have a good handle on it. Ah, my doctor showed me how to inject when I first started. And I called Lauren (my Nurse Ambassador) and she helped me the first few times I did it at home by myself.
SUPER:
Your healthcare provider should show you how to properly inject before you start injecting on your own.
Need a Nurse Ambassador?*
Call 1.866.SKYRIZI
Visit www.SKYRIZI.com
Or Live Chat 24/7 at
SkyriziComplete.com
*Nurse Ambassadors are provided by AbbVie and do not work under the direction of your health care professional (HCP) or give medical advice. They are trained to direct patients to their HCP for treatment-related advice, including further referrals.
[SKYRIZI logo]
SUPER:
INJECTION PREP
PATIENT V.O.:
Now, I get my SKYRIZI by mail and I keep it in the fridge until I’m ready to inject. Ah, there it is. There we go.
SUPER:
Do not warm SKYRIZI in any other way (for example, do not warm it in a microwave or in hot water).
PATIENT V.O.:
So, very important. I’ll leave it out at room temperature and out of direct sunlight for 30 to 90 minutes before injecting.
SUPER:
Do not use SKYRIZI if liquid has been frozen even if it has been thawed.
30 to 90 minutes.
Keep SKYRIZI in the original carton to protect from light until time to use.
PATIENT V.O.:
Now that I’ve washed and dried my hands, I’m good to go.
SUPER:
Do not shake SKYRIZI.
Do not use if the SKYRIZI Pen has been dropped or damaged.
Do not use SKYRIZI if package perforations are broken. Return product to the pharmacy.
Do not remove the dark gray cap until right before injection.
PATIENT V.O.:
So, I take out everything I need: Ah, I got my SKYRIZI Pen. I’ve got the Instructions for Use for reference. I’ve also got an alcohol swab, a cotton ball, and my Sharps container.
SUPER:
SKYRIZI PEN
INSTRUCTIONS FOR USE
ALCOHOL SWAB
Not included in your package
COTTON BALL
Not included in your package
SHARPS CONTAINER
PATIENT V.O.:
So, I do my injections here because there’s just plenty of light and a lot of good space.
SUPER:
Do not use SKYRIZI if expiration date (EXP) has passed.
SUPER:
HOW TO INJECT
step-by-step
PATIENT V.O.:
I like to think about the injection process like this…Pick. Pull. Place. Push. And press. So first...
SUPER:
PICK the injection site
PATIENT V.O.:
I’ll pick my injection site. I’m gonna go with my left thigh. But you can also inject into your stomach or your other thigh. If you choose your stomach, make sure that you inject at least two inches away from your belly button.
SUPER:
2 INCHES
PATIENT V.O.:
Grab your alcohol swab and clean your skin in a circular motion like this. And let it dry.
SUPER:
Do not touch or blow on the injection site after it is cleaned.
Allow the skin to dry before injecting.
PATIENT V.O.:
Now, I hold the Pen with the dark gray cap pointing up. I pull the cap straight off and throw it away.
SUPER:
PULL the cap off
Do not inject through clothes.
Do not inject into skin that is sore, bruised, red, hard, scarred, has stretch marks, or areas with psoriasis.
PATIENT V.O.:
Now I check the liquid through the inspection window. It should look clear to slightly yellow and may contain tiny white or clear particles. It’s normal to see one or more bubbles in the liquid.
SUPER:
Do not use if the liquid is discolored, cloudy, or contains flakes or large particles.
PATIENT V.O.:
So, I hold my Pen with my fingers on the gray grips. See? And I turn the Pen so that the white needle sleeve points toward my injection site and I can see the green activator button.
SUPER:
NEEDLE SLEEVE
PATIENT V.O.:
I also make sure that I can clearly see the inspection window while I’m injecting.
I gently squeeze my skin at my injection site and make a raised area and hold it firmly. Then I place the white needle sleeve straight against the raised area, at a 90-degree angle, and push the Pen down against my skin.
SUPER:
PLACE 90°
& PUSH against skin
PATIENT V.O.:
Throughout the process, I keep pinching the raised area and keep steady pressure against it. I can see the green activator button and inspection window. The Pen only activates if the white needle sleeve is pressed firmly down against me before pressing the green activator button.
SUPER:
PUSH against skin
The Pen will activate only if the white needle sleeve is firmly pushed down against the injection site before pressing the green activator button.
PATIENT V.O.:
A loud click means the start of the injection. There it goes.
SUPER:
PRESS the green button and keep steady pressure
Circle counting down from 15 to 0
PATIENT V.O.:
And hold it like that for 15 seconds. Now, I’ll keep pressing the Pen down against my skin until I hear a second click or the yellow indicator has filled the inspection window–either one signals the injection is complete. And there it goes. I check to make sure that the yellow indicator is fully down to be sure the injection is complete. Only then do I slowly pull the pen straight out from my skin. You might notice one last click. And look at this. You see how the white needle sleeve covers the needle tip?
And that’s it! Now I press a cotton ball where I injected. You could also use a gauze pad.
SUPER:
Press a cotton ball or gauze pad over the injection site and hold for 10 seconds. Do not rub the injection site. You may have slight bleeding. This is normal.
PATIENT V.O.:
And I drop my used Pen in one of these Sharps Disposal Containers.
SUPER:
Your Skyrizi Complete Sharps Disposal Container may look a little different than the one shown.
PATIENT V.O.:
There. Safe and sound and also out of reach. Another injection complete.
SUPER:
HELPFUL TIPS for self-injecting
PATIENT V.O.:
To recap, I prepare myself and my space. Pick an injection site. Pull the cap off the Pen. Place the Pen on the injection site. Push the Pen firmly down against my skin. Press the button to inject. And keep steady pressure on the injection site for the full 15 seconds.
Then safely discard the used Pen. That’s the whole injection process.
SUPER:
PICK the injection site
PULL the cap off
PLACE Pen on site
PUSH firmly down against skin
PRESS the button
DISCARD used Pen
PATIENT V.O.:
When I started injecting at home, it didn’t take me long to get it down. Lauren, my Nurse Ambassador, she suggested I create a routine. Inject at the same time and place. I also like to treat myself after each injection. And maybe I’ll cycle or listen to a new album.
And this Skyrizi Complete App helps me stay on track, and I don’t know what I’d do without it. I used it to log my first starter dose, so I knew when to take my second starter dose four weeks later.
And you can set reminders for future doses, too, since, after two starter doses, SKYRIZI is only 1 injection, 4 times a year.
SUPER:
1 INJECTION
4x A YEAR
PATIENT V.O.:
And when I get those reminders, I know to contact my specialty pharmacy to get my next injection on time.
I’m lucky that my family’s always around if I need help.
I’ve got Skyrizi Complete, too. Like Lauren, who has answers to my questions…
SUPER:
24/7 SUPPORT
Call 1.866.SKYRIZI
(1.866.759.7494)
Live Chat at SkyriziComplete.com
PATIENT V.O.:
…and a pretty awesome app.
You’ve got this.
SUPER/V.O.:
USES AND IMPORTANT SAFETY INFORMATION1
SKYRIZI® (risankizumab-rzaa) USES
SKYRIZI is a prescription medicine used to treat adults:
- with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).
- with active psoriatic arthritis (PsA).
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about SKYRIZI ® (risankizumab-rzaa)?
SKYRIZI is a prescription medicine that may cause serious side effects, including:
Serious allergic reactions:
Stop using SKYRIZI and get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction:
- fainting, dizziness, feeling lightheaded (low blood pressure)
- swelling of your face, eyelids, lips, mouth, tongue, or throat
- trouble breathing or throat tightness
- chest tightness
- skin rash, hives
- itching
Infections:
SKYRIZI may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI.
Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
- fever, sweats, or chills
- cough
- shortness of breath
- blood in your mucus (phlegm)
- muscle aches
- warm, red, or painful skin or sores on your body different from your psoriasis
- weight loss
- diarrhea or stomach pain
- burning when you urinate or urinating more often than normal
Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.
Before using SKYRIZI, tell your healthcare provider about all of your medical conditions, including if you:
have any of the conditions or symptoms listed in the section “What is the most important information I should know about SKYRIZI?”
have an infection that does not go away or that keeps coming back.
have TB or have been in close contact with someone with TB.
have recently received or are scheduled to receive an immunization (vaccine). Medications that interact with the immune system may increase your risk of getting an infection after receiving live vaccines. You should avoid receiving live vaccines right before, during, or right after treatment with SKYRIZI. Tell your healthcare provider that you are taking SKYRIZI before receiving a vaccine.
are pregnant or plan to become pregnant. It is not known if SKYRIZI can harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if SKYRIZI passes into your breast milk.
- become pregnant while taking SKYRIZI. You are encouraged to enroll in the Pregnancy Registry, which is used to collect information about the health of you and your baby. Talk to your healthcare provider or call 1-877-302-2161 to enroll in this registry.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of SKYRIZI? SKYRIZI may cause serious side effects. See “What is the most important information I should know about SKYRIZI?”
The most common side effects of SKYRIZI in people treated for plaque psoriasis and psoriatic arthritis include: upper respiratory infections, headache, feeling tired, injection site reactions, and fungal skin infections.
These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects.
Use SKYRIZI exactly as your healthcare provider tells you to use it.
SKYRIZI is available in a 150 mg/mL prefilled syringe and pen.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/PatientAccessSupport to learn more.
Reference: 1. SKYRIZI [package insert]. North Chicago, IL: AbbVie Inc.
US-SKZD-240413
[SKYRIZI logo]
SUPER/V.O.:
Please see link for the full Prescribing Information, including the Medication Guide, for SKYRIZI.
Special Warming Instructions:
First, take your SKYRIZI Pen out 30 to 90 minutes before injecting and leave the carton at room temperature, out of direct sunlight.
Once you wash and dry your hands and settle into a place where you feel relaxed, make sure you have everything laid out on a clean, flat surface.
You’ll need:
An alcohol swab, a cotton ball or gauze pad, your sharps container, which ensures your pen is disposed of safely, and of course, your SKYRIZI Pen.
A few things to look out for:
- DO NOT remove the Pen from the carton while allowing SKYRIZI to reach room temperature
- DO NOT warm SKYRIZI in any other way (for example, DO NOT warm it in a microwave or hot water)
- DO NOT use the Pen if liquid has been frozen, even if it has been thawed
Taking your SKYRIZI injection in 4 steps
A simple way to remember how to inject is with “4 P’s”:
Choose where you’re most comfortable with your injection:
- In the front of either thigh or in your stomach, at least 2 inches from your belly button
Once you wash and dry your hands:
- Settle into a relaxed place
- Wipe the injection site in a circular motion with the alcohol swab
- Let it dry
A few things to look out for:
- DO NOT touch or blow on the injection site after it is cleaned.
- Allow the skin to dry before injecting
- DO NOT inject through clothes
- DO NOT inject into skin that is sore, bruised, red, hard, scarred, has stretch marks, or areas with psoriasis
- Hold the Pen with the dark gray cap pointing up
- Pull the dark gray cap straight off
- Throw the dark gray cap away
Check the liquid through the inspection window
- It is normal to see one or more bubbles in the liquid
- The liquid should look clear to yellow and may contain tiny white or clear particles
- DO NOT use if the liquid is discolored, cloudy or contains flakes or large particles
- Hold the Pen with your fingers on the gray hand grips
- Turn the Pen so that the white needle sleeve points toward the injection site and you can see the green activator button
- Gently squeeze the skin at your injection site to make a raised area and hold it firmly
- Place the white needle sleeve straight (90° angle) against the raised injection site
- Hold the Pen so that you can see the green activator button and inspection window
- Push and keep pressing the Pen down against the pinched skin
The Pen will activate only if the white needle sleeve is pressed down.
- Press the green activator button and hold the Pen for 15 seconds
A loud “click” means the start of the injection.
- Keep pressing the Pen down against the injection site
The injection is complete when:
- The Pen has made a second “click”
or
- The yellow indicator has filled the inspection window
This takes up to 15 seconds.
When the injection is complete
- Slowly pull the Pen straight out from the skin
After completing the injection
- Place a cotton ball or gauze pad on the skin at the injection site
The white needle sleeve will cover the needle tip and make another “click.”
A few things to know:
- DO NOT rub the injection site
- Slight bleeding at the injection site is normal
Dispose of your Pen in a sharps disposal container.
Need a sharps container?
Skyrizi Complete can deliver one right to your door at no cost to you. Sign up or log in to access your Skyrizi Complete resources and order your container today.
Remember—do not throw your Pens away in the household trash. When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of it. There may be state or local laws about how you should throw away used needles and syringes.
For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at: www.fda.gov/safesharpsdisposal
- 1 full dose is 1 injection
- Store SKYRIZI in the refrigerator at 36° to 46°F (2° to 8°C)
- Keep SKYRIZI in the original carton to protect from light until you are ready to use
- Before injecting, take the SKYRIZI carton out of the refrigerator. Leave the carton at room temperature and out of direct sunlight for 30 to 90 minutes
- The liquid in the inspection window should look clear to yellow and may contain tiny white or clear particles
- DO NOT shake SKYRIZI
- DO NOT remove the dark gray cap until right before injection
- SKYRIZI is not made with natural rubber latex
Do not use your SKYRIZI Pen if:
- Liquid is discolored, cloudy or contains flakes or large particles
- Expiration date (EXP) has passed
- Liquid has been frozen, even if it has been thawed
- It has been dropped or damaged
- Carton perforations are broken. Return product to pharmacy
Self-guided plunger lets you activate and control the injection
You control the duration of your injection
Finger grips to help hold the syringe while injecting
Guard comes over the needle to let you know injection is finished
Guard comes over the needle to let you know injection is finished
Finger grips to help hold the syringe while injecting
You control the duration of your injection
Self-guided plunger lets you activate and control the injection
Watch the full video. Then choose a specific step from the menu above to watch any of sections again.
SUPER/VOICEOVER (V.O.):
This demonstration is a guide to injecting with the SKYRIZI prefilled syringe.
Watch it and also read the entire SKYRIZI Instructions for Use leaflet, inserted with your medication package.
Don’t try to inject SKYRIZI until your doctor has decided you can, and you’ve been shown the right way to inject.
SKYRIZI® (risankizumab-rzaa) USES
SKYRIZI is a prescription medicine used to treat adults:
- with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).
- with active psoriatic arthritis (PsA).
SAFETY CONSIDERATIONS
SKYRIZI may cause serious side effects, including:
- Serious allergic reactions: Stop using SKYRIZI and get emergency medical help right away if you get any symptoms of a serious allergic reaction.
- Infections: SKYRIZI may increase your risk of infections. Before starting treatment, your doctor should check you for infections and tuberculosis. Tell your doctor right away if you have an infection or symptoms of one.
Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI.
Also, tell your doctor if you plan to or recently received a vaccine.
SUPER:
[SKYRIZI logo]
Please see Use and Important Safety Information at the end of this video.
Please see link for the full Prescribing Information, including the Medication Guide, for SKYRIZI.
A GUIDE TO INJECTING SKYRIZI
[SKYRIZI logo]
[SKYRIZI Complete logo]
MAYA
PATIENT V.O.:
Hey there! I’m Maya and I’m here to walk you through how to inject yourself with SKYRIZI. Now, if it’s your first time, don’t worry! If it’s not your first time, I hope you pick up some new tips while you’re here.
Now, I’ve done this a few times by myself, but my doctor originally walked me through how to inject, and I called Bryan, who’s my Nurse Ambassador, when I first started injecting on my own at home.
SUPER:
Need a Nurse Ambassador?*
Call 1.866.SKYRIZI
Visit www.SKYRIZI.com
Or Live Chat 24/7 at
SkyriziComplete.com
*Nurse Ambassadors are provided by AbbVie and do not work under the direction of your health care professional (HCP) or give medical advice. They are trained to direct patients to their HCP for treatment-related advice, including further referrals.
[SKYRIZI logo]
SUPER:
INJECTION PREP
PATIENT V.O.:
Alright, let’s get started. So, when my SKYRIZI comes in the mail, it goes straight in the fridge. Now, before I inject, I let it sit out for 15 to 30 minutes, out of direct sunlight, to get to room temperature. And while I wait, I try to relax.
SUPER:
Do not warm SKYRIZI in any other way (for example, do not warm it in a microwave or in hot water).
Do not use SKYRIZI if liquid has been frozen even if it has been thawed.
15 to 30 minutes
Keep SKYRIZI in the original carton to protect from light until time to use.
PATIENT V.O.:
Okay, that should be enough time.
SUPER:
Do not shake SKYRIZI.
Do not use SKYRIZI if the syringe had been dropped or damaged.
Do not use SKYRIZI if package perforations are broken. Return product to the pharmacy.
Do not remove the needle cover until right before injection.
Do not use SKYRIZI if expiration date (EXP) has passed.
PATIENT V.O.:
So, once my hands are clean, I like to put out everything that I’ll need. So, I have my SKYRIZI syringe. I have an alcohol swab, which I got from my local pharmacy. I also have the Instructions for Use, just in case. And I also like to grab a cotton ball (I had some right in my medicine cabinet) and then a sharps container.
SUPER:
SKYRIZI SYRINGE
ALCOHOL SWAB not included in your package
INSTRUCTIONS FOR USE
COTTON BALL not included in your package
SHARPS CONTAINER
PATIENT V.O.:
Now, I like this spot because there’s a lot of space, and I don’t have to leave my couch.
SUPER:
HOW TO INJECT
step-by-step
SUPER:
So, it helps me to break down the injection process into 4 simple steps: the 4 Ps. And you can see them here on the package. We have: pick, prepare, pinch, push. Okay?
So, first I pick my injection site.
SUPER:
PICK the injection site
PATIENT V.O.:
So, I’ll go with my left thigh. But, you can also pick your right thigh or your lower stomach.
But, if you choose your stomach, make sure to inject at least 2 inches away from your belly button. Okay?
SUPER:
2 INCHES
PATIENT V.O.:
So, you want to grab your alcohol swab to clean your skin in a circular motion, like this, okay, and let it dry.
SUPER:
Do not touch or blow on the injection site after it is cleaned. Allow the skin to dry before injecting.
Remove prefilled syringe from cardboard sleeve by holding the finger grip.
PATIENT V.O.:
Now, I hold my syringe with the needle facing down, and I check the liquid inside to make sure that everything looks okay. So, it should be clear to slightly yellow, which it is. See that? And there’s a few bubbles in there, but that’s that’s normal. So looks like we’re good to go!
Alright, so I hold my syringe in one hand, and I take the needle cover off with the other hand. Okay?
SUPER:
PREPARE the syringe
Do not hold or pull plunger rod when removing the prefilled syringe from the sleeve.
Do not inject through clothes.
Do not inject into skin that is sore, bruised, red, hard, scarred, has stretch marks, or is affected by psoriasis.
Do not use if the liquid is discolored, cloudy or contains flakes or large particles.
Do not hold or pull plunger when removing the needle cover.
Do not touch the needle with your fingers or let the needle touch anything.
PATIENT V.O.:
Like this, and then you want to throw it away. You see? You may see a drop of liquid at the end of the needle, which is normal. Okay?.
So, I’ve got my syringe in one hand, and with the other hand, I’m gently pinching the area of my cleaned skin to hold firmly.
SUPER
PINCH the skin
PATIENT V.O.:
Now I’ll inject the needle into my skin at about a 45-degree angle using a quick, short movement–like this.
SUPER
PUSH
the plunger in
45°
PATIENT V.O.:
Now, holding the angle steady, I slowly push the plunger in all the way until all of the liquid is injected, and the syringe is empty. There we go.
Now, I pull the needle out of my skin while keeping the syringe at the same angle, like this, and I release the plunger to allow the syringe to move up... until the entire needle is covered up by the needle guard. See how that works? The needle guard won’t come back down unless all the liquid has been injected.
SUPER:
Press a cotton ball or gauze pad over the injection site and hold for 10 seconds.
Do not rub the injection site. You may have slight bleeding. This is normal.
PATIENT V.O.:
Alright, so now, I press my cotton ball where I just injected, and that’s it!
I drop my used syringe in one of these handy sharps disposal containers and—voila—safe and sound.
SUPER:
Your Skyrizi Complete Sharps Disposal Container may look a little different than the one shown.
PATIENT V.O.:
Now I’ll just put it back out of reach. And just like that, another injection complete!
SUPER:
HELPFUL TIPS for self-injecting
PATIENT V.O.:
So, to recap, I prepare myself and my space. I pick an injection site, prepare the syringe, pinch the skin, push the plunger in.
SUPER:
PICK the injection site
PREPARE the syringe
PINCH the skin
PUSH the plunger in
PATIENT V.O.:
And safely discard the syringe. That’s the whole injection process!
Now, it seemed tricky at first, but I got it down soon enough. And Bryan, my Nurse Ambassador, he recommended I create a routine–injecting at the same time, same place–that sort of thing. I also do something nice for myself after each injection–maybe I’ll paint as a reward.
Oh, and this Skyrizi Complete App has helped me so much.
I mean, I used it to log my first starter dose so I knew when to take my second starter dose 4 weeks later. You can set reminders for future doses, too since, after 2 starter doses, SKYRIZI is only 1 injection, 4 times a year.
SUPER:
1 INJECTION
4x A YEAR
PATIENT V.O.:
And when I get those reminders, I know to contact my specialty pharmacy to get my next injection on time.
I’m lucky to have people around to support me. I’ve got Skyrizi Complete on my team, too. Like Bryan, who’s such a good listener, and this App!
SUPER:
24/7 SUPPORT
Call 1.866.SKYRIZI
(1.866.759.7494)
Live Chat 24/7 at
SkyriziComplete.com
[SKYRIZI logo]
PATIENT V.O.:
There’s always someone to reach out to if you need help. You’ve got this.
SUPER/V.O.:
USES AND IMPORTANT SAFETY INFORMATION1
SKYRIZI® (risankizumab-rzaa) USES
SKYRIZI is a prescription medicine used to treat adults:
- with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).
- with active psoriatic arthritis (PsA).
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about SKYRIZI® (risankizumab-rzaa)?
SKYRIZI is a prescription medicine that may cause serious side effects, including:
Serious allergic reactions:
- Stop using SKYRIZI and get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction:
- fainting, dizziness, feeling lightheaded (low blood pressure)
- swelling of your face, eyelids, lips, mouth, tongue, or throat
- trouble breathing or throat tightness
- chest tightness
- skin rash, hives
- itching
Infections:
SKYRIZI may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI.
- Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
- fever, sweats, or chills
- cough
- shortness of breath
- blood in your mucus (phlegm)
- muscle aches
- warm, red, or painful skin or sores on your body different from your psoriasis
- weight loss
- diarrhea or stomach pain
- burning when you urinate or urinating more often than normal
Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.
Before using SKYRIZI, tell your healthcare provider about all of your medical conditions, including if you:
have any of the conditions or symptoms listed in the section “What is the most important information I should know about SKYRIZI?”
have an infection that does not go away or that keeps coming back.
have TB or have been in close contact with someone with TB.
have recently received or are scheduled to receive an immunization (vaccine). Medications that interact with the immune system may increase your risk of getting an infection after receiving live vaccines. You should avoid receiving live vaccines right before, during, or right after treatment with SKYRIZI. Tell your healthcare provider that you are taking SKYRIZI before receiving a vaccine.
are pregnant or plan to become pregnant. It is not known if SKYRIZI can harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if SKYRIZI passes into your breast milk.
become pregnant while taking SKYRIZI. You are encouraged to enroll in the Pregnancy Registry, which is used to collect information about the health of you and your baby. Talk to your healthcare provider or call 1-877-302-2161 to enroll in this registry.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of SKYRIZI?
SKYRIZI may cause serious side effects. See “What is the most important information I should know about SKYRIZI?”
The most common side effects of SKYRIZI in people treated for plaque psoriasis and psoriatic arthritis include: upper respiratory infections, headache, feeling tired, injection site reactions, and fungal skin infections.
These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects.
Use SKYRIZI exactly as your healthcare provider tells you to use it.
SKYRIZI is available in a 150 mg/mL prefilled syringe and pen.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/PatientAccessSupport to learn more.
Reference: 1. SKYRIZI [package insert]. North Chicago, IL: AbbVie Inc.
US-SKZD-240414
Please see link for the full Prescribing Information, including the Medication Guide, for SKYRIZI.
[SKYRIZI logo]
First, leave the carton at room temperature and out of direct sunlight for 15 to 30 minutes to warm.
Wash and dry your hands. Then, place your single-dose prefilled syringe and alcohol swab on a clean, flat surface.
You’ll also need:
- A cotton ball or gauze pad
- A sharps disposal container, which is a safe way to dispose of your syringe
A few things to look out for:
- DO NOT remove the syringe from the carton while allowing SKYRIZI to reach room temperature
- DO NOT warm SKYRIZI in any other way (for example, DO NOT warm it in a microwave or in hot water)
Taking your SKYRIZI injection in 4 steps
A simple way to remember how to inject is with “4 P’s”:
Choose where you’re most comfortable with your injection:
- In the front of either thigh or in your stomach, at least 2 inches from your belly button
Once you wash and dry your hands:
- Settle into a relaxed place
- Wipe the injection site in a circular motion with an alcohol swab before injecting
Do not touch or blow on the injection site after it is cleaned.
- Allow the skin to dry before injecting
A few things to look out for:
- DO NOT inject through your clothes
- DO NOT inject into skin that’s bruised, red, sore, scarred, hard, has stretch marks, or is affected by psoriasis
- DO NOT use SKYRIZI if the expiration date has passed
- DO NOT use SKYRIZI if liquid has been frozen, even if it has been thawed
- Hold the syringe with the covered needle facing down
- The liquid in the syringe should look clear to slightly yellow and may contain tiny white or clear particles. It is normal to see 1 or 2 bubbles
- Hold the syringe in 1 hand and gently pull the needle cover straight off with the other. Then throw it away
It’s normal to see a drop of fluid on the needle point
A few things to look out for:
- DO NOT use the prefilled syringe if the liquid is discolored, cloudy or has large particles or flakes
- DO NOT hold or pull the plunger when removing the needle cover
Remember not to touch the needle with your fingers or let the needle touch anything.
- Hold the body of the syringe in 1 hand, between the thumb and index finger
- With the other hand, gently pinch the area of cleaned skin and hold it
- Insert the needle at a 45-degree angle with a quick, short movement. Hold the angle steady
Something to look out for:
- DO NOT touch the needle with your fingers or let the needle touch anything
- Slowly push the plunger all the way down until all of the liquid is injected and the syringe is empty
- Gently pull the needle out of the skin while keeping the syringe at the same angle
- Release the plunger and allow the syringe to move up until the entire needle is covered by the needle guard
The syringe needle guard will not activate unless all the liquid has been injected.
- Press a cotton ball or gauze pad over your injection site for 10 seconds
Something to look out for:
- DO NOT rub the injection site.
- It’s normal to have some bleeding
Dispose of your syringe in a sharps disposal container.
Need a sharps container?
Skyrizi Complete can deliver one right to your door at no cost to you. Sign up or log in to access your Skyrizi Complete resources and order your container today.
A few things to look out for:
Remember not to throw your syringe away in the household trash. When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of it. There may be state or local laws about how you should throw away used needles and syringes.
For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at: www.fda.gov/safesharpsdisposal
- One full dose is only 1 injection
- You can store SKYRIZI in the refrigerator at 36°F to 46°F (2°C to 8°C). Keep SKYRIZI in the original carton to protect it from light until it’s time to use it
- Before injecting, leave the carton at room temperature and out of direct sunlight for 15 to 30 minutes to warm
- Keep your syringe in the carton while allowing SKYRIZI to reach room temperature—DO NOT try to warm your injection in hot water, in the microwave, or in any other way
- DO NOT remove the needle cover before you’re ready to give yourself your injection
Do not use your injection if:
- The liquid has been frozen, even if it was thawed
- The liquid is discolored, cloudy or contains flakes or large particles
- The expiration date (EXP) has passed
- The syringe has been dropped or damaged
- The syringe seal tray is broken. Return the product to the pharmacy