Tre

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Skyrizi®
risankizumab-rzaa

SKYRIZI is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).

SAFETY CONSIDERATIONS

SKYRIZI may cause serious side effects, including: 

• Serious allergic reactions: Stop using SKYRIZI and get emergency medical help right away if you get any symptoms of a serious allergic reaction. 

• Infections: SKYRIZI may increase your risk of infections. Before starting treatment, your doctor should check you for infections and tuberculosis. Tell your doctor right away if you have an infection or symptoms of one. 

Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI.  

Also, tell your doctor if you plan to or recently received a vaccine. 

Please see additional Important Safety Information near the end of this video. Please see link for the Full Prescribing Information, including the Medication Guide, for SKYRIZI.

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REAL PATIENT STORIES

Tre (V.O.):
I remember it was during summer…

Tre (V.O.):
…and it was actually at a pool party and I remember kinda noticing…

Tre:
…a little red mark on my chest. I was wondering…

Tre:
…did I scrape myself in the pool somehow?

Tre (V.O.):
But then, you know, the spot didn’t go away, and I noticed it started to spread more.

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MEET TRE

Tre (V.O.):
My name is Tre and I have…

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SKYRIZI is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).

Tre:
...moderate to severe plaque psoriasis.

Tre:
I think I’m so passionate about doing hair because I know what it feels like to…not be your best.

Tre (V.O.):
As someone who’s lived with psoriasis, I know how hard it is looking in the mirror. It was really…

Tre:
…difficult to keep the focus sometimes on the individual I was working with and not the symptoms that I was living with.

Tre (V.O.):
And I always hear that people don’t wanna look in the mirror for five minutes. So can you imagine…

Tre:
...eight hours of looking at yourself, every day? To keep my symptoms under control…

Tre:
…a typical day would start with me waking up about an hour and a half earlier than I normally would…

Tre (V.O.):
…and getting my topical steroid with a Q-tip…

Tre:
…and going over every single spot.

Tre (V.O.):
The doctor recommended I try SKYRIZI.

Tre (V.O.):
One of the things I love…

Tre:
…about SKYRIZI is the fact that my dosing’s once every three months.

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SKYRIZI IS 4 DOSES A YEAR
after 2 starter doses.

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Each dose of SKYRIZI is 1 injection.

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In clinical trials, 3 out of 4 people
ACHIEVED 90% CLEARER SKIN
at 4 months, after just 2 doses.

Tre (V.O.):
Within weeks, I started to see signs of the plaques…

Tre:
…disappearing, dissipating. I saw less…

Tre (V.O.):
…red marks. Even though every now and then….

Tre:
I may see a little bit of plaque coming out, I have to say that it is so minimal.

Tre:
I bet you guys can’t even see it.

Tre (V.O.):
Most days I forget I have psoriasis.

Tre (V.O.):
I know that looking in the mirror, I’m gonna feel confident…

Tre (V.O.):
…I’m gonna feel good…

Tre:
…and I’m gonna look gorgeous.

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“I’m going to look gorgeous.”

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Please continue watching for Important Safety Information.

V.O./On-Screen Text:

USE AND IMPORTANT SAFETY INFORMATION

SKYRIZI^® (risankizumab-rzaa) USE

SKYRIZI is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).

Important Safety Information

What is the most important information I should know about SKYRIZI^® (risankizumab-rzaa)?

SKYRIZI is a prescription medicine that may cause serious side effects, including: 

 Serious allergic reactions: 

• Stop using SKYRIZI and get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction: 
  -  fainting, dizziness, feeling lightheaded (low blood pressure)
  -  swelling of your face, eyelids, lips, mouth, tongue, or throat
  -   trouble breathing or throat tightness
  -  chest tightness
  -  skin rash, hives
  -  itching

Infections:
SKYRIZI may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI.

• Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
  - fever, sweats, or chills
  - cough
  - shortness of breath
  - blood in your mucus (phlegm)
  - muscle aches
  - warm, red, or painful skin or sores on your body different from your psoriasis 
  - weight loss
  - diarrhea or stomach pain
  - burning when you urinate or urinating more often than normal

• have any of the conditions or symptoms listed in the section “What is the most important information I should know about SKYRIZI?”
• have an infection that does not go away or that keeps coming back.
• have TB or have been in close contact with someone with TB.
• have recently received or are scheduled to receive an immunization (vaccine). Medications that interact with the immune system may increase your risk of getting an infection after receiving live vaccines. You should avoid receiving live vaccines right before, during, or right after treatment with SKYRIZI. Tell your healthcare provider that you are taking SKYRIZI before receiving a vaccine.
• are pregnant or plan to become pregnant. It is not known if SKYRIZI can harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if SKYRIZI passes into your breast milk.
• become pregnant while taking SKYRIZI. You are encouraged to enroll in the Pregnancy Registry, which is used to collect information about the health of you and your baby. Talk to your healthcare provider or call 1-877-302-2161 to enroll in this registry.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.  

What are the possible side effects of SKYRIZI? 

SKYRIZI may cause serious side effects. See “What is the most important information I should know about SKYRIZI?”

The most common side effects of SKYRIZI in people treated for plaque psoriasis and psoriatic arthritis include: upper respiratory infections, feeling tired, fungal skin infections, headache, and injection site reactions.  

These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects. 

Use SKYRIZI exactly as your healthcare provider tells you to use it.  

SKYRIZI is available in a 150 mg/mL prefilled syringe and pen. 

Please see the Full Prescribing Information, including the Medication Guide, for SKYRIZI.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

© 2023 AbbVie. All rights reserved. SKYRIZI^® and its design are registered trademarks of AbbVie Biotechnology Ltd.