Injection Support

Ready to inject? Let’s get started.

Once you and your doctor have talked about at-home injections, resources like the video and steps below are available to walk you through the steps of administering your injections successfully.

You can get additional information from the SKYRIZI medication guide here.

Your Skyrizi Complete Nurse Ambassador* can help

Whenever you want injection training support, your Nurse Ambassador is there to help. At no cost to you, they can take you through the training you received from your doctor—all at a pace that’s comfortable for you.
 

Don’t have a Nurse Ambassador? Sign up for Skyrizi Complete.

*Nurse Ambassadors do not give medical advice and will direct you to your healthcare professional for any treatment-related questions, including further referrals.

Looking for Specific Injection Information?

Use the topics below to jump to each section.

 

Preparing for your SKYRIZI injection

First, wash your hands, then place your two prefilled syringes and two alcohol swab­s on a clean, flat surface.

Items needed before injection including two cotton balls, two alcohol swabs, and one Skyrizi Sharps Container Items needed before injection including two cotton balls, two alcohol swabs, and one Skyrizi Sharps Container Items needed before injection including two cotton balls, two alcohol swabs, and one Skyrizi Sharps Container

Bring your injection to room temperature by removing the carton from the refrigerator 15 to 30 minutes before your injection. Keep the carton out of direct sunlight.

You’ll also need two cotton balls or gauze pads and a sharps disposal container, which is the safest way to dispose of your syringes.

 

Taking your SKYRIZI injection

Pick the injection site
Illustration of two SKYRIZI injection site options: abdomen (around belly button) or front of either thigh Illustration of two SKYRIZI injection site options: abdomen (around belly button) or front of either thigh Illustration of two SKYRIZI injection site options: abdomen (around belly button) or front of either thigh

You choose where you’re most comfortable with your injections—either in front of your thigh or in your abdomen at least two inches from your belly button. Your second injection should be injected at least one inch away from the first one.

Wipe the injection site in a circular motion with an alcohol swab before both injections. Do not touch or blow on the injection site after it is cleaned. Allow the skin to dry before injecting.

Remember not to inject through your clothes or onto skin that’s bruised, red, sore, scarred, hard, has stretch marks, or is affected by psoriasis. Do not inject into the same site.

Prepare the syringe
Pinch the skin
Push the plunger in
Remember: repeat

 

After your injection

Illustration of SKYRIZI injection being properly disposed of in a Skyrizi Sharps Container Illustration of SKYRIZI injection being properly disposed of in a Skyrizi Sharps Container Illustration of SKYRIZI injection being properly disposed of in a Skyrizi Sharps Container

Dispose of both syringes in a sharps disposal container. Need a sharps container? No problem. Skyrizi Complete can deliver one right to your door at no cost to you.

Sign up for access to your Skyrizi Complete resources.

Don’t throw your syringe away in the household trash.

When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of your sharps disposal container. There may be state or local laws about how you should throw away used needles and syringes.

For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at:

 

Important things to know about your injection

  • One full dose is two injections.
  • You can store SKYRIZI in the refrigerator at 36° F to 46° F. Keep SKYRIZI in the original carton to protect it from light until it’s time to use it.
  • Before injecting, leave the carton at room temperature and out of direct sunlight for 15 to 30 minutes to warm.
  • Keep the syringes in the carton while allowing SKYRIZI to reach room temperature. Don’t try to warm your injection in hot water, in the microwave, or in any other way.
  • Don’t remove the needle cover before you’re ready to give yourself your injection.

Do Not Use Your Injection if:

  • The liquid has been frozen, even if it was thawed.
  • The liquid is cloudy or contains flakes or large particles.
  • The expiration date (EXP) has passed.
  • The syringe has been dropped or damaged.
  • The syringe seal tray is broken or missing. Return the product to the pharmacy.

Your Skyrizi Complete Nurse Ambassador can help make injections a part of your normal routine.

Need help now?
Call 1.866.SKYRIZI (1.866.759.7494)

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Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

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SKYRIZI may cause serious side effects. See “What is the most important information I should know about SKYRIZI?”

The most common side effects of SKYRIZI include upper respiratory infections, fungal skin infections, headache, feeling tired, and injection site reactions.

These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects.

Use SKYRIZI exactly as your healthcare provider tells you to use it.

US-RISN-180038

Please see the Full Prescribing Information, including the Medication Guide, for SKYRIZI.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit

or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

Legal Notices/Privacy Policy. Copyright 2019, AbbVie Inc., North Chicago, Illinois, U.S.A. If you have any questions about AbbVie’s SKYRIZI.com website that have not been answered, click here. This website and the information contained herein is intended for use by US residents only, is provided for informational purposes only and is not intended to replace a discussion with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider and consider the unique characteristics of each patient.

USE

SKYRIZI is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking

IMPORTANT SAFETY INFORMATION

SKYRIZI may cause serious side effects, including infections. SKYRIZI is a prescription medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB)

IMPORTANT SAFETY INFORMATION

SKYRIZI may cause serious side effects, including infections. SKYRIZI is a prescription medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with

USE

SKYRIZI is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).

IMPORTANT SAFETY INFORMATION

SKYRIZI may cause serious side effects, including infections. SKYRIZI is a prescription medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI. Tell

IMPORTANT SAFETY INFORMATION

SKYRIZI may cause serious side effects, including infections. SKYRIZI is a prescription medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with

USE USE for SKYRIZI™ (risankizumab-rzaa)

SKYRIZI is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about SKYRIZI™ (risankizumab-rzaa)?

SKYRIZI may cause serious side effects, including infections. SKYRIZI is a prescription medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI.

  • Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
    • fever, sweats, or chills
    • muscle aches
    • weight loss
    • cough
    • warm, red, or painful skin or sores on your body different from your psoriasis
    • diarrhea or stomach pain
    • shortness of breath
    • blood in your mucus (phlegm)
    • burning when you urinate or urinating more often than normal

Before using SKYRIZI, tell your healthcare provider about all of your medical conditions, including if you:

  • have any of the conditions or symptoms listed in the section “What is the most important information I should know about SKYRIZI?”
  • have an infection that does not go away or that keeps coming back.
  • have TB or have been in close contact with someone with TB.
  • have recently received or are scheduled to receive an immunization (vaccine). You should avoid receiving live vaccines during treatment with SKYRIZI.
  • are pregnant or plan to become pregnant. It is not known if SKYRIZI can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if SKYRIZI passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of SKYRIZI?

SKYRIZI may cause serious side effects. See “What is the most important information I should know about SKYRIZI?”

The most common side effects of SKYRIZI include upper respiratory infections, fungal skin infections, headache, feeling tired, and injection site reactions.

These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects.

Use SKYRIZI exactly as your healthcare provider tells you to use it.

US-RISN-180038

Please see the Full Prescribing Information, including the Medication Guide, for SKYRIZI.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit

or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

Legal Notices/Privacy Policy. Copyright 2019, AbbVie Inc., North Chicago, Illinois, U.S.A. If you have any questions about AbbVie’s SKYRIZI.com website that have not been answered, click here. This website and the information contained herein is intended for use by US residents only, is provided for informational purposes only and is not intended to replace a discussion with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider and consider the unique characteristics of each patient.

© 2019 AbbVie Inc.