Steve

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SKYRIZI is a prescription medicine used to treat adults with active psoriatic arthritis (PsA).

SAFETY CONSIDERATIONS

SKYRIZI may cause serious side effects including:

  • Serious allergic reactions: Stop using SKYRIZI and get emergency medical help right away if you get any symptoms of a serious allergic reaction. 
  • Infections: SKYRIZI may increase your risk of infections. Before starting treatment, your doctor should check you for infections and tuberculosis. Tell your doctor right away if you have an infection or symptoms of one. 

Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI.  

Also, tell your doctor if you plan to or recently received a vaccine. 

Please see additional Important Safety Information near the end of this video. Please see link for the Full Prescribing Information, including the Medication Guide, for SKYRIZI.

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Skyrizi®
risankizumab-rzaa

Steve:
Well I've played guitar since I was eight years old.

Steve:
When I get a little down or I have extra time on my hands, I can just escape with it.  

Steve:
My name is Steve and I have active psoriatic arthritis.

Steve:
I first experienced my skin problems when I was 28 years old.  

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1 IN 3 PEOPLE
WITH PSORIASIS MAY ALSO DEVELOP PSORIATIC ARTHRITIS  

Steve:
My doctor told me since I have plaque psoriasis, I might develop psoriatic arthritis.  

Steve:
I was starting to have joint pains.   

Steve:
I had them in the hips. I had them in the elbows,…

Steve:
…in the knees.  

Steve:
And as time went on it got more consistent, a little more painful.  

Steve:
And, I just lived with it. And then finally it was to the point where I couldn’t live with it anymore.

Steve:
I went to my local dermatologist and I described…  

Steve:
…my symptoms. And then, when he found out more about my history,…

Steve:
…he put all the pieces together…

Steve:
…and immediately diagnosed psoriatic arthritis.

Steve:
The plaque psoriasis affected me because… 

Steve:
…people can see it.

Steve:
That hurts your self-esteem. 

Steve:
The psoriatic arthritis,…

Steve:
…there it’s more of a personal thing.

Steve:
It’s internal. Everything feels real tight…

Steve:
…and feels stiff. 

Steve:
Normal life becomes a little more difficult,…

Steve:
…whether you’re mowing the lawn, or whether you’re going out fishing. 

Steve:
I tried oral treatments. 

Steve:
I tried a couple different things. 

Steve:
And then I ended up on SKYRIZI. 

Steve:
As I tried SKYRIZI, I started to feel better. 

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LESS JOINT PAIN, STIFFNESS,
AND SWELLLING 

In PsA clinical trials, a majority experienced a 20% improvement in symptoms at week 24.

Steve:
My joint symptoms improved in a few months. 

Steve:
I feel less pain when I'm getting ready in the morning.  

Steve:
When everything started improving, I started to become a believer.  

Steve:
After six months,…

Steve:
…I was truly a believer.

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90% CLEARER SKIN
IN PATIENTS WHO ALSO HAD  
PLAQUE PSORIASIS

In PsA clinical trials, a majority of those who also had plaque psoriasis saw 90% clearer skin at week 24. 

Steve:
My doctor told me I had reached 90% clearance.

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90% CLEARER SKIN
IN PATIENTS WHO ALSO HAD  
PLAQUE PSORIASIS

In PsA clinical trials, a majority of those who also had plaque psoriasis saw 90% clearer skin at week 24. 

Steve:
I noticed I had fewer plaques.  
After six months…

Steve:
…most of the plaques were gone.

Steve:
It’s really important that you seek out treatment as soon as you realize you have any symptoms at all.

Steve:
Ask him what causes it, what are my options,…

Steve:
…and where can I go from there.

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SKYRIZI LOGO

V.O./On-Screen Text:
IMPORTANT SAFETY INFORMATION AND USE

SKYRIZI® (risankizumab-rzaa) USE

SKYRIZI is a prescription medicine used to treat adults with active psoriatic arthritis (PsA).

Important Safety Information

What is the most important information I should know about SKYRIZI®
(risankizumab-rzaa)?

SKYRIZI is a prescription medicine that may cause serious side effects, including: 

Serious allergic reactions:

  • Stop using SKYRIZI and get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction: 
    -  fainting, dizziness, feeling lightheaded (low blood pressure)
    -  swelling of your face, eyelids, lips, mouth, tongue, or throat
    -   trouble breathing or throat tightness
    -  chest tightness
    -  skin rash, hives
    -  itching

Infections:
SKYRIZI may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI.

  • Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
    - fever, sweats, or chills
    - cough
    - shortness of breath
    - blood in your mucus (phlegm)
    - muscle aches
    - warm, red, or painful skin or sores on your body different from your psoriasis 
    - weight loss
    - diarrhea or stomach pain
    - burning when you urinate or urinating more often than normal

Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients. 

Before using SKYRIZI, tell your healthcare provider about all of your medical conditions, including if you: 

  •  have any of the conditions or symptoms listed in the section “What is the most important information I should know about SKYRIZI?”
  • have an infection that does not go away or that keeps coming back. 
  • have TB or have been in close contact with someone with TB. 
  • have recently received or are scheduled to receive an immunization (vaccine). Medications that interact with the immune system may increase your risk of getting an infection after receiving live vaccines. You should avoid receiving live vaccines right before, during, or right after treatment with SKYRIZI. Tell your healthcare provider that you are taking SKYRIZI before receiving a vaccine. 
  • are pregnant or plan to become pregnant. It is not known if SKYRIZI can harm your unborn baby. 
  • are breastfeeding or plan to breastfeed. It is not known if SKYRIZI passes into your breast milk.
  • become pregnant while taking SKYRIZI. You are encouraged to enroll in the Pregnancy Registry, which is used to collect information about the health of you and your baby. Talk to your healthcare provider or call 1-877-302-2161 to enroll in this registry.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.  

What are the possible side effects of SKYRIZI? 

SKYRIZI may cause serious side effects. See “What is the most important information I should know about SKYRIZI?”

The most common side effects of SKYRIZI in people treated for plaque psoriasis and psoriatic arthritis include: upper respiratory infections, headache, feeling tired, injection site reactions, and fungal skin infections. 

These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects.

Use SKYRIZI exactly as your healthcare provider tells you to use it.  

SKYRIZI is available in a 150 mg/mL prefilled syringe and pen. 

Please see the Full Prescribing Information, including the Medication Guide, for SKYRIZI.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

© 2023 AbbVie. All rights reserved. SKYRIZI® and its design are registered trademarks of AbbVie Biotechnology Ltd.

US-SKZD-220724

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Skyrizi®
risankizumab-rzaa