What is SKYRIZI?
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SKYRIZI is a biologic prescription for adults with moderate to severe plaque psoriasis and for adults with active psoriatic arthritis.
SKYRIZI (Sky-RIZZ-ee; skaɪ rɪz zi) is an interleukin-23 (IL-23) inhibitor that works inside the body to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy) and for adults with active psoriatic arthritis. The exact cause of plaque psoriasis and psoriatic arthritis are unknown.
Talk to your doctor to see if SKYRIZI may be right for you.
- Do you feel soreness or pain in your joints?
- Do you feel stiffness and swelling in your joints? If so, where?
- Are you having trouble standing or gripping?
If you answered yes, you could be experiencing symptoms of psoriatic arthritis (PsA). Ask your doctor if SKYRIZI may be right for you.
SKYRIZI may cause serious side effects, including serious allergic reactions. Stop using SKYRIZI and get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction:
- fainting, dizziness, feeling lightheaded (low blood pressure)
- swelling of face, eyelids, lips, mouth, tongue, or throat
- trouble breathing or throat tightness
- chest tightness
- skin rash, hives
SKYRIZI may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI. Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
- fever, sweats, or chills
- shortness of breath
- blood in your mucus (phlegm)
- muscle aches
- warm, red, or painful skin or sores on your body different from your psoriasis
- weight loss
- diarrhea or stomach pain
- burning when you urinate or urinating more often than normal
Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI.
The most common side effects of SKYRIZI include:
These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects.
Use SKYRIZI exactly as your healthcare provider tells you to use it.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.