SKYRIZI
DOSING

ONLY 6 DOSES A YEAR
AFTER 3 STARTER DOSES

SKYRIZI can fit into your schedule with at home dosing every 8 weeks, after a total of 3 intravenous (IV) starter doses and proper training from your healthcare professional.

3 Starter Doses

Dose Timeline for Weeks 0, 4, and 8

600 mg intravenous infusion per dose

Only 1 Dose Every 8 Weeks

Dose Timeline for Weeks 16, 24, and 32

360 mg/2.4 mL subcutaneous injection via OBI

Adults with Crohn’s disease will receive their starter doses with SKYRIZI through a vein in the arm (intravenous infusion) in a healthcare facility by a healthcare provider. After completing the starter doses, patients will receive SKYRIZI as an injection under the skin (subcutaneous injection) using the prefilled cartridge with the On-Body Injector (OBI).

After Training, You Can Take Control of Your Treatment Experience With the SKYRIZI On-Body Injector (OBI)

See the SKYRIZI “Instructions for Use” for the full set of detailed instructions on the preparation and administration of SKYRIZI.

Here are the 5 P’s to help you remember:

1

PREPARE

Gather alcohol wipes, gauze pads or cotton balls, and sharps disposal container.

2

PICK

Pick a place on the thigh or abdomen to inject.

3

PEEL

Peel the 2 green pull tabs to reveal the adhesive without touching the needle.

4

PLACE

Place the OBI onto the skin. Ensure that the status light is visible.

5

PRESS

Press and release the gray start button to begin. A flashing green light will appear. When the injection is complete the green light goes solid.

Designed With You In Mind

Compact Icon

COMPACT SIZE

Small enough to fit in the palm of the hand.

Hidden Icon

HIDDEN NEEDLE

Discreet injection so you don’t see the needle.

Notify Icon

AUDIO AND VISUAL CUES

Notifies when full dose has been delivered.

Hands-Free Icon

HANDS-FREE

While adhered to the body and after activation. Moderate physical activities can be done such as walking, reaching, and bending.

5 Minutes Icon

DOSE DELIVERED IN 5 MINUTES

Completes the injection in set time after preparation and application are complete.

In a patient survey,

93% of patients reported the OBI was “Easy To Use” after the first use

In an ongoing survey of the SKYRIZI On-Body Injector (OBI), patient-reported experience was collected using a Self-Injection Assessment Questionnaire (SIAQ). Patients were given the questionnaire after injection training by a healthcare provider (HCP) and following their first self-injection. 42 out of 45 patients reported the OBI was either “easy” or “very easy” to use.

HOW TO USE SKYRIZI: See the detailed “Instructions for Use” that comes with SKYRIZI for information on how to prepare and inject a dose of SKYRIZI, and how to properly throw away (dispose of) a used SKYRIZI prefilled cartridge with On-Body Injector. Before self-injecting with SKYRIZI prefilled cartridge with On-Body Injector, your healthcare provider should show you how to inject SKYRIZI.

Support at Every Step

Skyrizi Complete is dedicated to providing personalized support at every step of your treatment.

How IT
Works

SKYRIZI works differently by specifically targeting a protein called interleukin-23 (IL-23), which is one of the key proteins responsible for inflammation. By targeting IL-23, SKYRIZI can help to reduce the excess inflammation that may contribute to Crohn’s symptoms.

SKYRIZI targeting IL-23 protein in foreground